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Glut3 molecular weight

WebApr 5, 2024 · GLUT3 controls the effector function of Th17 cells. To investigate the function of GLUT3 in T cells, we generated mice with T cell-specific inactivation of the Slc2a3 … WebSep 2, 2024 · Under glucose-limiting conditions, GLUT3 expedited CRC cell growth by accelerating glucose input and fuelling nucleotide synthesis. Notably, GLUT3 had a greater impact on cell growth than GLUT1 under glucose-limiting stress. Mechanistically, low-glucose stress dramatically upregulated GLUT3 via the AMPK/CREB1 pathway.

Molecular basis for inhibiting human glucose transporters by

Web1-氧杂-8-氮杂-螺[4,5]癸-3-酮1-Oxa-8-aza-spiro[4.155.19432133382-42-... WebJul 15, 2015 · The crystals of GLUT3 in the presence of d-glucose were obtained in the P2 1 Fig. 1c, Extended Data Fig. 2a–d and Extended Data Table 1). The transmembrane region of GLUT3 exhibits a canonical ... new kitchenaid dishwasher door twerking https://spencerslive.com

Recombinant Human Glucose Transporter GLUT3 protein (ab152681)

Web蛋白分子量 predicted molecular weight: 114kDa. 性 状 Lyophilized or Liquid. 免 疫 原 KLH conjugated synthetic peptide derived from human EphA6/Eph receptor A6. 亚 型 IgG 酪氨酸蛋白激酶受体 A6 抗体 我司提供以下技术外包服务: 1. WebImmunoblots of brain membrane preparations showed that both antisera identified peptide-inhibitable protein bands of molecular weight 45,000-50,000. Immunocytochemical studies demonstrated that binding sites for these antisera were abundantly distributed in neuropil in all brain regions. WebMar 9, 2024 · The mouse GLUT3 gene encodes a 493-amino acid protein with a predicted molecular weight of ∼54 kDa, and in this study GLUT3 was detected at ∼66 kDa in mouse sciatic nerve and muscle (Supplementary Fig. 2B). new kitchenaid attachments

Recombinant Human Glucose Transporter GLUT3 protein (ab152681)

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Glut3 molecular weight

The glucose transporter GLUT3 controls T helper 17 cell responses ...

WebMay 12, 2024 · Phase was solved by molecular replacement using PHASER 44 with the structure of GLUT3 (PDB code: 4ZW9) as a searching model. The model was rebuilt in … WebGLUT3 was detected in the syncytiotrophoblast at all gestational ages by immunohistochemistry. Using Western blotting GLUT3 was detected as an integral …

Glut3 molecular weight

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WebApr 6, 2024 · GLUT3 expression is reported in monocytes and T lymphocytes in the human immune system , and in activated T lymphocytes in ... As previously reported we noted that GLUT3 protein aggregates to form high molecular weight smears in Western blot of boiled lysate and that copy number dependent protein levels at 54 kDa could only be observed … WebJan 26, 2024 · The identified GLUT3 inhibitors had IC 50 values between ~ 7 and 38 µM for GLUT3 (Fig. 2, Table 2), and between ~ 6 and 25 µM in GLUT3 S66Y (Supplementary …

WebNational Center for Biotechnology Information WebJan 26, 2024 · The identified GLUT3 inhibitors had IC 50 values between ~ 7 and 38 µM for GLUT3 (Fig. 2, Table 2), and between ~ 6 and 25 µM in GLUT3 S66Y (Supplementary Fig. S3, Supplementary Table S2).

WebJun 22, 1998 · Western blot analysis of the rat brain revealed that the antiserum detected a strong band with a molecular weight of 45 kDa and a weak band of about 55 kDa, which corresponded respectively to the known molecular weights of the GLUT1 proteins in the brain parenchymal cells and the brain microvessels. WebThe molecular weight of GLUT3 transporter is 49-52 kDa and depends on the glycosylation pattern, which is tissue-specific (PMID: 9253355 and …

Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans is encoded by the SLC2A3 gene. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT3 is most known for its … See more GLUT3 was the third glucose transporter to be discovered, first cloned in 1988 from a fetal skeletal muscle cell line, using a GLUT1 cDNA probe and shown to share 64.4% identity with GLUT1. See more Click on genes, proteins and metabolites below to link to respective articles. See more Although GLUT3 was found to be expressed in various tissues, it is most specifically expressed in neurons, found predominantly in axons and dendrites and also, but less … See more • Glucose+Transporter+Type+3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more

WebJan 9, 2024 · Glucose Transporter Glut3 Antibody (G-5) is an IgG1 κ mouse monoclonal Glut3 antibody that detects m, r, and h Glut3 by WB, IP, IF and ELISA. 39 citations ... new kitchenaid dishwasher not spraying waterWebDec 20, 2014 · We noticed that Glut3 signals occurred as high molecular weight smears when samples were boiled, and therefore we incubated samples at room temperature for 30 minutes. Protein blotting was performed using the iBlot system (Invitrogen). new kitchenaid dishwasher model kudp01flss3WebGLUT3 is one of fourteen facilitative sugar transporters, which use the glucose diffusion gradient to move across various plasma membranes to display various specificities, ... in time for the friends reunionWebMay 1, 2024 · The gene quantification was performed using the following commercially available probes from Thermo Fisher Scientific: Rpl30 (Mm01611464_ g1, used for normalization), Glut1 ( Slc2a1) (Mm00441480_m1), Glut3 ( Slc2a3) (Mm00441483_m1), Arg1 (Mm00475988_m1), Hk2 (Mm00443385_ m1), Siglecf ( Siglec5) … new kitchenaid dishwasher not opening fullyWebMar 21, 2024 · We found that the glucose transporter GLUT3 is essential for the effector functions of Th17 cells in models of autoimmune colitis and encephalomyelitis. At the molecular level, we show that GLUT3-dependent glucose uptake controls a metabolic-transcriptional circuit that regulates the pathogenicity of Th17 cells. in time for schoolWebOct 31, 2024 · We created a neural-specific conditional murine glut3 ( Slc2A3 ) deletion ( glut3 flox/flox/nestin-Cre+) to examine the effect of a lack of Glut3 on neurodevelopment. Compared with age-matched glut3 flox/flox = WT and heterozygotes ( glut3 flox/+/nestin-Cre+), we found that a >90% reduction in male and female brain Glut3 occurred by … in time for sthWebIn this study, we have demonstrated that in rat brain, GLUT3 is found exclusively in the neuronal/glial fraction and is absent from cerebral microvessels, whereas GLUTl is detected as different molecular weight forms in each fraction. new kitchenaid black appliances 2017